En este libro Pedro Karczmarczyk se da a la tarea de recopilar ―además de colaborar con un texto propio― una serie de artículos que abordan las principales tradiciones de la filosofía contemporánea, en especial sobre un tema que se encuentra en el meollo del pensamiento filosófico: la cuestión del sujeto. Podemos pensar entonces que el título, El sujeto en cuestión, evoca de manera certera lo común que atraviesa la diversidad de enfoques; volviéndose el hilo de Ariadna que nos ayuda a (...) caminar por un laberinto poblado de gigantes filosóficos que, como es su célebre y problemática costumbre, hablan su propio idioma. Este cuestionamiento sobre la multívoca categoría de ‘sujeto’ (vocablo que ha sido entendido como sustrato-súbdito-sujeto de la consciencia entre otros) comienza con la necesaria ruptura respecto del espíritu filosófico moderno que creyó fervientemente en la posibilidad de delimitar ―y agotar― los modos y los medios a través de los cuales la consciencia (el sujeto) es capaz de representar el mundo. Cénit de este modo de pensar fue la filosofía de Kant, referente ineludible de muchos de los autores analizados en el presente libro que de un modo u otro se enfrentan a la pretensión fundacionista, ahistoricista y universalista de nuestro pasado filosófico. (shrink)

Dentro de la sociología francesa actual, Gilles Lipovetsky se ha convertido de forma paulatina en uno de los sociólogos con mayor proyección internacional, con sus finos análisis sobre las sociedades postmodernas. En este artículo se plantea una revisión crítica de las principales líneas argumentativas que expone el autor francés. El objetivo es el de reflexionar sobre las limitaciones de su aproximación a los conceptos de postmodernidad, hipermodernidad, y consumo.

The objective of this research is to develop accurate forecasting models for chlorophyll-α concentrations at various depths in El Mar Menor, Spain. Chlorophyll-α plays a crucial role in assessing eutrophication in this vulnerable ecosystem. To achieve this objective, various deep learning forecasting techniques, including long short-term memory, bidirectional long short-term memory and gated recurrent uni networks, were utilized. The models were designed to forecast the chlorophyll-α levels with a 2-week prediction horizon. To enhance the models’ accuracy, a sliding window method (...) combined with a blocked cross-validation procedure for time series was also applied to these techniques. Two input strategies were also tested in this approach: using only chlorophyll-α time series and incorporating exogenous variables. The proposed approach significantly improved the accuracy of the predictive models, no matter the forecasting technique employed. Results were remarkable, with |$\overline{\sigma}$| values reaching approximately 0.90 for the 0.5-m depth level and 0.80 for deeper levels. The proposed forecasting models and methodologies have great potential for predicting eutrophication episodes and acting as decision-making tools for environmental agencies. Accurate prediction of eutrophication episodes through these models could allow for proactive measures to be implemented, resulting in improved environmental management and the preservation of the ecosystem. (shrink)

Despite abundant evidence associating CD38 overexpression and CD4 T cell depletion in HIV infection, no causal relation has been investigated. To address this issue, a series of mechanisms are proposed, supported by evidence from different fields, by which CD38 overexpression can facilitate CD4 T cell depletion in HIV infection. According to this model, increased catalytic activity of CD38 may reduce CD4 T cells’ cytoplasmic nicotin‐amide adenine dinucleotide (NAD), leading to a chronic Warburg effect. This will reduce mitochondrial function. Simultaneously, CD38's (...) catalytic products ADPR and cADPR may be transported to the cytoplasm, where they can activate calcium channels and increase cytoplasmic Ca2+ concentrations, further altering mitochondrial integrity. These mechanisms will decrease the viability and regenerative capacity of CD4 T cells. These hypotheses can be tested experimentally, and might reveal novel therapeutic targets. (shrink)

Business knowledge management is a crucial element and a quality differentiator in the services provided by organizations. However, despite their knowledge, due to the lack of strategic knowledge management, reinsurance companies in Colombia limit their organizational development, their strategies to respond to competition, and the generation of opportunities for expansion into other markets. This issue may converge in an inadequate and non-harmonic organizational culture. This paper analyzes and interprets the study categories: prevention, mitigation, transfer, acceptance, research, and appropriation of knowledge (...) on management carried out by reinsurance organizations in Bogota, Colombia. The aim is to establish indicators that respond to the potential effects of reinsurance. The study uses a qualitative approach, descriptive scope, and case study design. From the formulation of improvement guidelines, it has been possible to establish that the companies in the reinsurance sector, taken as a unit of study, have been made aware of the importance and role of adequate knowledge management in the progress and the business projection. (shrink)

Los centros de educación superior son por definición espacios de generación de conocimiento, derivado de ello se vincula la aplicación de los valores primordiales que rigen el desarrollo académico y científico. Entre estos valores subyacen tales como honestidad, justicia, respeto, responsabilidad y confianza. Existen múltiples interpretaciones de integridad académica, este estudio se promueve el cual abarca todos los elementos mencionados como valores básicos del desarrollo social y universitario: honestidad, justicia, respeto, responsabilidad y confianza.Este estudio se orienta a conocer el grado (...) de transparencia, compromiso e integridad presente en las universidades en el desarrollo de su labor académica e investigadora. (shrink)

The introduction of the notion of family resemblance represented a major shift in Wittgenstein’s thoughts on the meaning of words, moving away from a belief that words were well defined, to a view that words denoted less well defined categories of meaning. This paper presents the use of the notion of family resemblance in the area of machine learning as an example of the benefits that can accrue from adopting the kind of paradigm shift taken by Wittgenstein. The paper presents (...) a model capable of learning exemplars using the principle of family resemblance and adopting Bayesian networks for a representation of exemplars. An empirical evaluation is presented on three data sets and shows promising results that suggest that previous assumptions about the way we categories need reopening. (shrink)

El texto pretende señalar un recorrido cronológico por algunas de las obras más importantes de Theodor Adorno. Con ello se procura mostrar cómo en su filosofía, desde sus inicios hasta su última gran obra, hubo un desarrollo coherente en el cual el arte llegó a configurarse como un modelo crítico de la razón ilustrada, en tanto que él puede acoger y representar lo excluido, y por ello coartado, por la racionalidad instrumental.

El objetivo central de este artículo consiste en argumentar a favor de la tesis de que es imposible o, al menos, excesivamente difícil evaluar creencias basadas en la memoria, especialmente cuando se justifican en los denominados recuerdos episódicos, lo que implica que las creencias basadas en la memoria episódica no pueden ser justificadas suficientemente para alcanzar el estatus de conocimiento. Para lograr este objetivo expondré brevemente las diferencias y las relaciones que hay entre memoria, recuerdo, creencia y conocimiento (o saber). (...) Posteriormente presentaré diversas formas en que ha sido entendida la memoria, así como algunas de las pruebas que han servido para medir la memoria ya que en función de estas se puede mantener que hay recuerdos falsos. Aunque estas pruebas son valiosas para los propósitos para las que fueron diseñadas, hay casos que se les escapan y estos tienen implicaciones epistemológicamente importantes, entre ellas que la memoria episódica no es una fuente confiable para justificar algunas de nuestras creencias y que estas cuenten como conocimiento. (shrink)

In recent years, the term populism has become indeed popular. Among its variants, a very particular one stands out. It is the so-called managerial populism, in which prominent businessmen have entered the arena of politics with a program focused on the regeneration of economic and social life. Donald Trump, perhaps, has been the most outstanding example. In this article, our aim is to analyze this phenomenon of managerial populism, addressing a number of issues. Firstly, we will discuss the emergence of (...) a certain type of charismatic leadership in business or management ideologies as a development that largely precedes the consolidation of these figures in the political scene; the implications of these ideologies in the political and social sphere; and the importance of the forms of discursive use of the concept of people in these popular discourses. (shrink)

El artículo ofrece un panorama del precedente en el Civil Law con el objetivo de distinguir los problemas que pueden presentarse en los sistemas jurídicos que tienen una práctica formal o institucionalizada de precedente, de aquellos en los que no la hay. Se identificó que se introdujo el precedente como una forma de responder a las crecientes demandas de administración de justicia en la materia y delimitar la discrecionalidad del operador jurídico. Por tanto, la tesis de fondo de este trabajo (...) es que, en la operación regular de los sistemas jurídicos del Civil Law, tanto los tribunales constitucionales y la jurisdicción en general identificaron la necesidad práctica de dotar de contornos a los derechos humanos —en tanto disposiciones jurídicas a concretar jurisdiccionalmente—. (shrink)

For companies involved in the supply chain, proper warehousing management is crucial. Warehouse layout arrangement and operation play a critical role in a company’s ability to maintain and improve its competitiveness. Reducing costs and increasing efficiency are two of the most crucial warehousing goals. Deciding on the best warehouse layout is a remarkable optimization problem. This paper uses an optimization method to set bin allocations within an automated warehouse with particular characteristics. The warehouse’s initial layout and the automated platforms limit (...) the search and define the time required to move goods within the warehouse. With the help of historical data and the definition of the time needed to move goods, a mathematical model of warehouse operation was created. An optimization procedure based on the well-known Variable Neighbourhood Search algorithm is defined and applied to the problem. Experimental results demonstrate increments in the efficiency of warehousing operations. (shrink)

Researchers from diverse disciplines, including organismal and cellular physiology, sports science, human nutrition, evolution and ecology, have sought to understand the causes and consequences of the surprising variation in metabolic rate found among and within individual animals of the same species. Research in this area has been hampered by differences in approach, terminology and methodology, and the context in which measurements are made. Recent advances provide important opportunities to identify and address the key questions in the field. By bringing together (...) researchers from different areas of biology and biomedicine, we describe and evaluate these developments and the insights they could yield, highlighting the need for more standardisation across disciplines. We conclude with a list of important questions that can now be addressed by developing a common conceptual and methodological toolkit for studies on metabolic variation in animals. (shrink)

Psychological flexibility is a key concept of acceptation and commitment therapy. This factor has been linked with psychological wellbeing and associated factors, such as quality of life, in cancer patients. These and other positive results of acceptation and commitment therapy in cancer patients found in previous research could be enhanced by using mhealth tools. A three-arm randomized superiority clinical trial, with a pre-post-follow-up repeated measures intergroup design with a 1:1:1 allocation ratio is proposed. A hundred and twenty cancer patients will (...) be randomly assigned to one of the following interventions: face-to-face ACT + mobile application, face-to-face ACT, and Waitlist control group. The primary expected outcome is to observe significant improvements in psychological flexibility acceptance and action questionnaire- II in the face-to-face ACT + app group, after comparing baseline and post-treatment scores, and the scores will remain stable in the two assessment points, 3 and 6 months after the intervention. Secondary expected outcomes are significant increasing scores in quality of life and post-traumatic-growth, and significant decreasing scores in anxiety and depression, insomnia and fatigue at the same assessment points. Also, it is expected that the scores of this group will be higher than the scores of the face-to-face ACT group and the waitlist control group. This study aims to assess the efficacy of a combined intervention for psychological flexibility and associated symptoms in cancer patients. The results of this protocol may help to consider the use of acceptation and commitment therapy and mhealth applications in cancer settings as a valid therapeutic choice.Clinical Trial Registration[www.ClinicalTrials.gov], identifier [NCT05126823]. (shrink)

Este artículo explora los recursos narrativos y visuales planteados en el cómic colombiano, desde 1992 hasta nuestros días, para describir representaciones distópicas de la ciudad de Bogotá. La distopía se entiende, en términos generales, como una visión negativa, para la humanidad, de un futuro posible o de un presente alterno, y se clasifica acá en distopías de fallo tecnológico, distopías de coerción simbólica/ coerción física, distopías de apocalipsis zombie/infectado y distopías de apocalipsis sobrenatural/no humano. Para la investigación se recopilaron las (...) publicaciones impresas disponibles desde 1992, de los cuales se seleccionaron aquellos que sucedieran o hicieran referencia a la ciudad de Bogotá. De los 45 cómics que cumplían dicho criterio, se identificaron y analizaron las 28 piezas que presentaron un escenario distópico. Entre los hallazgos fundamentales se encontró que la violencia y el conflicto, tanto simbólicos como físicos, son constantes en los diferentes escenarios distópicos identificados en la muestra, lo que refleja y proyecta la violencia histórica que vive un país como Colombia. (shrink)

Antibiotic use triggers evolutionary and ecological responses from bacteria, leading to antibiotic resistance and harmful patient outcomes. Two complementary strategies support long-term antibiotic effectiveness: conservation of existing therapies and production of novel antibiotics. Conservation encompasses infection control, antibiotic stewardship, and other public health interventions to prevent infection, which reduce antibiotic demand. Production of new antibiotics allows physicians to replace existing drugs rendered less effective by resistance.In recent years, physicians and policymakers have raised concerns about the pipeline for new antibiotics, pointing (...) to a decline in the number of antibiotics approved since the 1980s. This trend has been attributed to high research and development costs, low reimbursement for antibiotics, and regulatory standards for review and approval. Professional societies and researchers around the world have called for renewed emphasis on antimicrobial stewardship, while also supporting antibiotic research and development through grants, changes to intellectual property laws to extend market exclusivity periods, and modification of premarket testing regulations to reduce antibiotic development time and expenses. (shrink)

The goal of this essay is to expose the foundations of Enrique Dussel’s philosophy of liberation and to explain its contributions in the context of Latin-american thinking. In a postmetaphysical level of foundation, the philosophy of liberation adopts the ethos from semitic thinking and the Levinas’ hermeneutics of the «Other» with the proposal of formulate a criticism of eurocentrism and to build an alternative philosophical model. In front of the traditional paradigms of philosophy and philosophical historiography, Enrique Dussel (...) develops a new arquitectonics to report on the specificity of our thinking. (shrink)

The epistemes of human beings enter into crisis with their practice. They make evident their inability to have known each other; while its expeditious complexity is: nature-body-mind-soul-spirit-God. As a research objective, we support transepistemes to think about human beings in planetary decoloniality-complexity. The trans prefix inherits concepts from the legacy of Enrique Dussel. We investigate in the midst of wonderful transmethodologies, in the lines of research titled: planetary decoloniality-complexity in re-linkage; complex transmethodologies and planetary-complex decolonial transmethods. With the transmethod (...) of rhizomatic deconstruction we achieve transepistemes such as: human beings are the creation of God, transepisteme the root of all; the spirit comes from the breath of life of the creation given by God to the clay in Adam; the human being is political, gregarious and he can reform his thinking. Insanity, evil, lack of solidarity are not part of creation, but come from sin; which is incited by humanism, transhumanism and the attack on the nature of creation with the support of artificial intelligence. (shrink)

El artículo estudia el sintagma 'membrana et atramentum' en la obra agustiniana, para descubrir, a través de una lectura conjunta del corpus agustiniano, las diversas implicaciones que este sintagma conlleva en los aspectos semántico, semiótico y teológico.

El artículo es una crónica del "colloquium" celebrado en la "Academia Belgica" de Roma, del 15 al 17 de septiembre de 2011, acerca de los sermones agustinianos "ad populum" sobre el Nuevo Testamento. El artículo hace una presentación general de cada una de las contribuciones presentadas en el "colloquium", acentuando su aportación a los estudios agustinianos.

El presente artículo analiza sucintamente la redención como expresión de la soteriología agustiniana, formulada en cuanto descenso de Cristo hacia los hombres, tal y como este movimiento de abajamiento se retrata en diversas "Enarrationes in Psalmos", haciendo particular hincapié en las imágenes usadas por Agustín o en los misterios a los que él hace referencia, al hablar del descenso de Cristo para salvar a los hombres.

El artículo aborda la cuestión de la versión de los salmos que usban los donatistas. Para ello el artículo parte, en primer lugar, del análisis de los textos de los salmos que han quedado recogido en el Liber Regularum de Ticonio y que se encuentran también en los Testimonia de san Cipriano, concretamente los salmos 2, 23 y 90, haciendo una comparación de dichos textos con los de san Cipriano y san Agustín. Posteriormente se abordan los salmos que san Agustín (...) pone en boca del obispo donatista Petiliano en el segundo libro de su obra Contra Litteras Petiliani. Se estudian únicamente los salmos cuyo texto es presentado por completo, a saber: 1, 2, 22 y 132. En cada uno de ellos se refiere el texto tal y como es presentado por Petiliano en la obra, posteriormente se hace la comparación de dicho texto con el de san Cipriano y el de san Agustín. El artículo destaca y comenta el contexto de las citas, así como sus semejanzas y diferencias. Finalmente se abordan los salmos que nos ofrece Optato de Milevi como pertenecientes a la pars donati, haciendo la comparación con el texto de los salmos tal y como nos los refiere san Cipriano en sus Testimonia y la versión de san Agustín en las enarrationes in Psalmos. (shrink)

En el presente artículo se presentan los espectáculos del anfiteatro tal y como aparecen en las obras de san Agustín, poniendo de manifiesto las diversas implicaciones y significados que para él tiene el anfiteatro, particularmente lo relativo a quienes llenan esos lugares y a la valoración que le merecen a san Agustín los espectáculos ahí desarrollados. Posteriormente se habla de la figura de los gladiadores, lo que representan para san Agustín, y de la utilización catequética en sus sermones.

El artículo ofrece en su primera parte una visión sinóptica de la labor de san Agustín como predicador, así como de la difusión de sus obras, y de las primeras ediciones impresas de estas, hasta llegar a las ediciones críticas actuales. La segunda parte presenta los últimos hallazgos de documentos agustinianos: las cartas Divjak, los sermones Dolbeau y los sermones Erfurt, a propósito de los cuales hace una amplia introducción, a la que sigue el análisis resumido del contenido de cada (...) uno de ellos. (shrink)

El artículo estudia la expresión "poculum tuum obliuionem praestans" en los escritos de San Agustín, presentando la interpretación que el obispo de Hipona hace del salmo 22 en las Enarrationes in Psalmos.

The article deals with Augustine’s soteriological ideas, with which he tries to fight against Donatism trying to reestablish Peace, underlining the importance of the dead of Christ as Redeemer, taking as point of departure the text of Psalm 21, 28-29, to demonstrate the universality of salvation against the Donatist’s concept of Redemption. The article underlines the main Soteriological and Ecclesiological ideas of St. Augustine, making the comparison between the text of Psalm 22 used by Augustine, the Text of the Vulgata (...) and the one used by Cyprian within his Testimonia ad Quirinum. Finally the importance of Peace is underlined, focusing on the Elogium pacis that Augustine presents in the enarratio to Psalm 147. (shrink)

This paper shows that, for a large range of parameters, the journal editor prefers to delegate the choice to review the manuscript to the biased referee. If the peer review process is informative and the review reports are costly for the reviewers, even biased referees with extreme scientific preferences may choose to become informed about the manuscript’s quality. On the contrary, if the review process is potentially informative but the reviewer reports are not costly for the referees, the biased reviewer (...) has no incentive to become informed about the manuscript. Furthermore, if the reports are costly for referees but the peer review processes are not potentially informative, the biased reviewers will never become informed. In this paper, we also present a web resource that helps editors to experiment with the review process as a device for information transmission. (shrink)

There are many real-world applications like healthcare systems, job monitoring, well-being and personal fitness tracking, monitoring of elderly and frail people, assessment of rehabilitation and follow-up treatments, affording Fall Detection (FD) and ADL (Activity of Daily Living) identification, separately or even at a time. However, the two main drawbacks of these solutions are that most of the times, the devices deployed are obtrusive (devices worn on not quite common parts of the body like neck, waist and ankle) and the poor (...) battery life. Thus, this work proposes a low-power classification algorithm based on an Ensemble of KNN and K-Means algorithms (EKMeans) to identify Falls and High-Intensity ADL events such as running, jogging and climbing up stairs. The input of EKMeans are triaxial accelerometer data gathered from wrist-wearable devices. The proposal will be validated on the Fall&ADL publicly available datasets UMAFall, UCIFall and FallAllD, considering two kinds of activity labelling: Two-Class and Multi-Class. An exhaustive comparative study between our proposal, and the baseline algorithms KNN and a feed-forward Neural Network (NN) is deployed, where EKMeans outperformed clearly the Specificity (ADL classification) of the KNN and NN for the three datasets. Finally, a comparative battery consumption study has been included deploying the analyzed algorithms in a WearOS smartwatch, where EKMeans drains the battery from 100% to 0% in 27.45 hours, saving 5% and 21% concerning KNN and NN, respectively. Keywords: Human Activity Recognition, ADL Identification, Fall Detection TS Clustering, TS Classification, Wearable Devices, Low-Power HAR. (shrink)

El artículo presenta, en primer lugar, una introducción al libro VIII del De Genesi ad litteram. Posteriormente pone de manifiesto sus principales temas exegéticos y teológicos. Se aborda en primera instancia, la recensión que hace san Agustín de los diversos comentarios anteriores a él sobre el tema del paraíso, así como su propia propuesta exegética. Se aborda asimismo la cuestión de la creación, el árbol del bien y del mal, la interpretación del trabajo del hombre en el jardín del Edén, (...) destacando la importancia y la dilogía del verbo latino colo (dar culto, cultivar). El artículo aborda asimismo la cuestión de la providencia divina, y se destacan los elementos trinitarios, cristológicos y antipelagianos que pueden encontrarse en el libro VIII del De Genesi ad litteram. Todos estos argumentos son abordados haciendo referencia a los comentarios agustinianos anteriores al libro del Génesis, particularmente el De Genesi aduersus manicheos y el De Genesi ad litteram imperfectus liber. (shrink)

El artículo estudia la obra "De sancta uirginitate" desde un punto de vista eclesiológico, superando así la opinión según la cual sólo las mujeres consagradas a Dios son destinatarias de ella. Comenta también la polémica sobre la uirginitas a finales del siglo IV y principios del siglo V, y cómo presenta la virginidad el pensamiento agustiniano.

The first part of the article presents some aspects of Augustinian interiority, highlighting those characteristics that are most forgotten or ignored today, pointing out that despite the Platonic and Neoplatonic influences, St. Augustine was not converted to the truths of Platonism, but to the truths of Christianity, without denying the influence that Platonic and Neoplatonic ideas had on the thought of St. Augustine, particularly from his contact with the “Milanese Neoplatonic circle”. The article points out that St. Augustine goes beyond (...) the philosophical “spiritual exercises” to emphasize the fundamental role of grace in the whole spiritual journey. To be able to leave the world of exteriority and return to one’s inner self will always be a gift from God. Subsequently, the text of beata u. 35 is analysed, highlighting the importance of the admonitiones of God, through the Holy Spirit, to return to one’s inner self, as well as the characteristics of the encounter with God, since the God discovered in one’s own heart is Triune God. It is emphasized how many of the expressions and vocabulary in these Augustinian disquisitions are taken from the anti-Arian writings of Marius Victorinus. Subsequently, the text of sol. 1, 2-3 is analysed, in order to highlight not only the importance of the Holy Spirit, who invites us to return to the interior, but also the particularities of the encounter with the Father and the Son, pointing out the various characteristics that distinguish them. (shrink)